The best Side of ceesdekker
The best Side of ceesdekker
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It was only from the 1990s while, when nanotechnology had State-of-the-art to a stage where solitary molecules might be manipulated, that the 1st experimental devices started to look.
‘It was simply just a make any difference of finding up a e book on cell biology and starting to browse. I'd come from a world of extremely-large vacuums, cryostats and quantum phenomena, and now I was Doing the job at place temperature with molecular biology kits.
Non-equilibrium folding of individual DNA molecules recaptured up to 1000 times inside a strong state nanopore
2010, produced a whole new way (‘wedging transfer’) to govern nanostructures; to start with report of DNA translocation through graphene nanopores; and realized hybrid nanopores by directed insertion of α-hemolysin into sound-condition nanopores
Cornelis (Cees) Dekker (Haren, seven april 1959) is een Nederlandse natuurkundige en universiteitshoogleraar verbonden aan de Technische Universiteit Delft. Van 2010 tot en fulfilled 2018 was hij tevens directeur van het Kavli Institute of Nanoscience in Delft. Zijn vakgebied is de moleculaire biofysica; hierbij beweegt hij zich op het grensvlak van de natuurkunde en de biologie waarbij hij gebruikmaakt van de zogeheten nanotechnologie, de technieken om aan enkele atomen en moleculen te kunnen meten.
A lot of relevant developments adopted, the place our group proven diverse transistor variants for instance one-electron transistors at place temperature and intramolecular nanotube junctions that cees dekker acted as rectifying diodes, and coupled many transistors into compact evidence-of-basic principle Digital circuits.
Learning DNA loop extrusion by SMC proteins for chromosome architecture with single-molecule assays.
‘Certainly, I comprehend people today had been astonished at time. At the conclusion of the nineties, when I was in my forties, I used to be Professor of Molecular Electronics and I've to admit that it had turn into a bit bored, I didn’t find out A great deal any more. The sector went extra into the application aspect, how you could integrate nanotubes into electronic circuits.
Resolving the move size in condensin-pushed DNA loop extrusion identifies ATP binding given that the move-building system
An integrated microfluidic System for quantifying drug permeation throughout biomimetic vesicle membranes
‘That worries the artificial cell, as Component of the Dutch BaSyC initiative. Craig Venter looked prime-down in those days and determined about 5 hundred genes which can be minimally demanded to get a operating mobile. We want to search base-up: how can we move from a several molecules to an entire biological technique?
Visualization of unstained DNA nanostructures with Sophisticated in-target transmission electron microscopy approaches
Stable-point out nanopores have demonstrated to generally be a shockingly multipurpose probe for one-molecule Assessment of DNA. I'll explain a number of our modern results – especially DNA knots – along with our attempts to increase the capabilities of solid-point out nanopores even further more, during the way of solitary-protein detection, graphene nanopores, plasmonic nanopores, and DNA origami nanopores.